BDBM50425387 CHEMBL2311806
SMILES Cc1cn(cn1)-c1cc(C)cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)c1
InChI Key InChIKey=KVTMDRDZMBVWNC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50425387
TargetPlatelet-derived growth factor receptor beta(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKd: 12nMAssay Description:Binding affinity to human PDGFRbeataMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKd: 65nMAssay Description:Binding affinity to human PDGFRalphaMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKd: 1.20E+3nMAssay Description:Binding affinity to human FLT3More data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKd: 5.60nMAssay Description:Binding affinity to human DDR2More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKd: 14nMAssay Description:Binding affinity to human c-KitMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataKd: 3.40nMAssay Description:Binding affinity to human ABL1More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 136nMAssay Description:Inhibition of human ABL1 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human PDGFRalpha using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of human LYN using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of human LCK using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 882nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human DDR2 using KKSRGDYMTMQIG peptide substrateMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 768nMAssay Description:Inhibition of human PDGFRbeta using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair