BDBM50426567 BMS-204352::FLINDOKALNER::MaxiPost
SMILES COc1ccc(Cl)cc1[C@]1(F)C(=O)Nc2cc(ccc12)C(F)(F)F
InChI Key InChIKey=ULYONBAOIMCNEH-HNNXBMFYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50426567
TargetPotassium voltage-gated channel subfamily KQT member 5(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataEC50: 2.40E+3nMAssay Description:Positive modulatory activity at voltage-gated K channel 7.5 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataEC50: 2.40E+3nMAssay Description:Positive modulatory activity at voltage-gated K channel 7.4 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 3(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataEC50: 2.40E+3nMAssay Description:Positive modulatory activity at voltage-gated K channel 7.3 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataEC50: 2.40E+3nMAssay Description:Positive modulatory activity at voltage-gated K channel 7.2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetCalcium-activated potassium channel subunit alpha-1(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataEC50: 352nMAssay Description:Positive modulation of Kca 1.1 (unknown origin)More data for this Ligand-Target Pair