BDBM50426570 CHEMBL2324344

SMILES CCCC(=O)C1CCN(CC1)c1ncnc2CCN(Cc12)C(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=CJZGRIRZVHNUSM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50426570   

TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50:  300nMAssay Description:Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50:  35nMAssay Description:Inhibition of TASK-3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50:  300nMAssay Description:Inhibition of TASK-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50:  35nMAssay Description:Inhibition of human TASK3 expressed in HEK293 cells by Qpatch HT platform based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50:  243nMAssay Description:Inhibition of human TASK3 expressed in Xenopus oocytes by whole cell voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 9(Rattus norvegicus)
Universidad De Talca

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50:  10nMAssay Description:Inhibition of rat TASK3 expressed in (FRT) epithelial cells by chamber based electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
University Of Kansas Specialized Chemistry Center

Curated by ChEMBL
LigandPNGBDBM50426570(CHEMBL2324344)
Affinity DataIC50:  300nMAssay Description:Inhibition of human TASK1 expressed in HEK293 cells by Qpatch HT platform based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed