BDBM50427512 AURIN::CI-43800::Corallin::Rosolic acid::Rosolic acid (18)

SMILES [#8]-c1ccc(cc1)-[#6](=[#6]-1\[#6]=[#6]-[#6](=O)-[#6]=[#6]-1)\c1ccc(-[#8])cc1

InChI Key InChIKey=FYEHYMARPSSOBO-UHFFFAOYSA-N

Data  2 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50427512   

TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50427512(AURIN | CI-43800 | Corallin | Rosolic acid | Rosol...)
Affinity DataKi:  1.43E+3nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier organic anion transporter family member 1B3(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50427512(AURIN | CI-43800 | Corallin | Rosolic acid | Rosol...)
Affinity DataKi:  3.15E+3nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear factor NF-kappa-B p105 subunit(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50427512(AURIN | CI-43800 | Corallin | Rosolic acid | Rosol...)
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier organic anion transporter family member 1B3(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50427512(AURIN | CI-43800 | Corallin | Rosolic acid | Rosol...)
Affinity DataIC50:  4.07E+3nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM50427512(AURIN | CI-43800 | Corallin | Rosolic acid | Rosol...)
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50427512(AURIN | CI-43800 | Corallin | Rosolic acid | Rosol...)
Affinity DataIC50:  2.63E+3nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed