BDBM50428697 CHEMBL2333119::US9884828, 4-188
SMILES CC(C)Nc1c(nnc2cc(ccc12)N1CCN(C)CC1)C(N)=O
InChI Key InChIKey=JSGNHFVUNFUTOO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50428697
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Imago Pharmaceuticals
US Patent
Imago Pharmaceuticals
US Patent
Affinity DataIC50: 53nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Imago Pharmaceuticals
US Patent
Imago Pharmaceuticals
US Patent
Affinity DataIC50: 53nMAssay Description:Inhibition of wild type GST-tagged LRRK2 (970 to 2527 amino acid residues) (unknown origin) assessed as inhibition of biotinylated-LRRKtide phosphory...More data for this Ligand-Target Pair