BDBM50429763 CHEMBL229844::N-(4-Hydroxyphenyl)Cinnamamide::US11135207, Example 4
SMILES Oc1ccc(NC(=O)\C=C\c2ccccc2)cc1
InChI Key InChIKey=WSRJZGPYPSPGLJ-IZZDOVSWSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50429763
Target72 kDa type IV collagenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine
Curated by ChEMBL
Nanjing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human recombinant MMP2 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Nanjing University Of Chinese Medicine
Curated by ChEMBL
Nanjing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human recombinant MMP1 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Nanjing University Of Chinese Medicine
Curated by ChEMBL
Nanjing University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human recombinant MMP9 using succinylated gelatin as substrate incubated for 30 mins prior to substrate addition measured after 60 minsMore data for this Ligand-Target Pair