BDBM50430339 CHEMBL2333879

SMILES CN(C)c1nc(nc2ccc(cc12)-c1cn[nH]c1)[C@@H]1CNC[C@H]1c1ccccc1

InChI Key InChIKey=QQWMBNHFQAYFPP-VQTJNVASSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50430339   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50430339(CHEMBL2333879)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant 6-His-tagged ROCK2 expressed in baculovirus-infected Sf9 cells using LCB-AKRRRLSSLRA-NH2 as substrate after 25 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase MRCK alpha(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50430339(CHEMBL2333879)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50430339(CHEMBL2333879)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50430339(CHEMBL2333879)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50430339(CHEMBL2333879)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50430339(CHEMBL2333879)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed