BDBM50430982 CHEMBL2337863

SMILES Oc1cccn(Cc2cn(nn2)-c2ccccc2)c1=S

InChI Key InChIKey=SKRDXBWAVNFLCE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50430982   

TargetHistone deacetylase 8(Homo sapiens (Human))
Georgia Tech Research

US Patent
LigandPNGBDBM50430982(CHEMBL2337863)
Affinity DataIC50:  1.57E+3nMT: 2°CAssay Description:Fluor de Lys is a fluorescence based HDAC activity assay comprising a combination of fluorogenic Histone deAcetylase Lysyl substrate and a developer....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Georgia Tech Research

US Patent
LigandPNGBDBM50430982(CHEMBL2337863)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of HDAC8 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) using GRKacFGC as substrate after 60 mins by SAMDI mas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Georgia Tech Research

US Patent
LigandPNGBDBM50430982(CHEMBL2337863)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) after 60 mins by SAMDI spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed