BDBM50431866 CHEMBL2347476
SMILES CCc1nc(CC)n2CCN([C@@H](C(=O)NC)c3ccccc3)C(CCc3ccc(cc3)C(F)(F)F)c12
InChI Key InChIKey=GAWATXZDBWIYHK-XSWBTSGESA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50431866
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human OX2 receptor expressed in CHO cells assessed as inhibition of orexin A-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Actelion Pharmaceuticals
Curated by ChEMBL
Actelion Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human OX1 receptor expressed in CHO cells assessed as inhibition of orexin A-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair