BDBM50432520 CHEMBL2349486

SMILES CC(=O)N1CCC(CN2C(N)=NC3(CC(C)(C)Oc4ccc(cc34)-c3cccc(Cl)c3)C2=O)CC1

InChI Key InChIKey=ZWVDHKMVDCTBOB-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432520   

TargetBeta-secretase 1(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50432520(CHEMBL2349486)
Affinity DataEC50:  75nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing wild type APP assessed as level of amyloid beta (1 to 40) after 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed