BDBM50432546 CHEMBL2349496

SMILES CN1C(N)=NC2(CC(C)(C)Oc3ccc(cc23)-c2cccc(OC(F)F)c2)C1=O

InChI Key InChIKey=VQNCDPHEWAYVDD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432546   

TargetBeta-secretase 1(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50432546(CHEMBL2349496)
Affinity DataEC50:  88nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing wild type APP assessed as level of amyloid beta (1 to 40) after 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed