BDBM50432768 CHEMBL2348634

SMILES C[C@H](C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1)c1ccccc1

InChI Key InChIKey=HEVUROULBIHFRC-AWEZNQCLSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50432768   

TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50432768(CHEMBL2348634)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Cryptosporidium IMPDH preincubated for 10 mins before substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50432768(CHEMBL2348634)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50432768(CHEMBL2348634)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University

Curated by ChEMBL
LigandPNGBDBM50432768(CHEMBL2348634)
Affinity DataIC50:  900nMAssay Description:Inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed