BDBM50433570 CHEMBL2381571

SMILES CN1CCC[C@H]1COC(=O)c1ccc(Br)cc1

InChI Key InChIKey=SFSMPEDWDOLQDX-LBPRGKRZSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50433570   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile

Curated by ChEMBL
LigandPNGBDBM50433570(CHEMBL2381571)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile

Curated by ChEMBL
LigandPNGBDBM50433570(CHEMBL2381571)
Affinity DataKi:  1.05E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile

Curated by ChEMBL
LigandPNGBDBM50433570(CHEMBL2381571)
Affinity DataIC50:  78nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile

Curated by ChEMBL
LigandPNGBDBM50433570(CHEMBL2381571)
Affinity DataIC50:  2.11E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed