BDBM50434120 OXINDOLE

SMILES O=C1Cc2ccccc2N1

InChI Key InChIKey=JYGFTBXVXVMTGB-UHFFFAOYSA-N

Data  3 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50434120   

TargetChymase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50434120(OXINDOLE)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50434120(OXINDOLE)
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human PDHK4 assessed as reduction in acetyl-coenzymeA formation by RapidFire mass spectrometryMore data for this Ligand-Target Pair
LigandPNGBDBM50434120(OXINDOLE)
Affinity DataIC50:  9.58E+5nMAssay Description:Inhibition of human PDHK2 assessed as reduction in acetyl-coenzymeA formation by RapidFire mass spectrometryMore data for this Ligand-Target Pair