BDBM50436001 CHEMBL2392174::CHEMBL2425818
SMILES COc1ccc(cc1)C(=O)Nc1cc(Br)cc2c1oc(cc2=O)C(O)=O
InChI Key InChIKey=TZKQFDIFVZAYER-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50436001
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKd: 5.70nMAssay Description:Competitive binding affinity to human recombinant GPR35 expressed in CHO cells by scintillation counting analysis in presence of MgCl2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKd: 115nMAssay Description:Binding affinity to human recombinant GPR35 expressed in CHO cells by scintillation counting analysis in absence of MgCl2, NaCl, CaCl2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKd: 5.30nMAssay Description:Binding affinity to human recombinant GPR35 expressed in CHO cells after 150 mins by liquid scintillation counting analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at human GPR35 expressed in CHO-K1 cells after 90 mins by beta-arrestin 2 recruitment assayMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Agonist activity at human GPR35b expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase report...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Agonist activity at rat GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporter ...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair
Affinity DataKd: 5.90nMAssay Description:Competitive binding affinity to human recombinant GPR35 expressed in CHO cells by scintillation counting analysis in presence of CaCl2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.17E+4nMAssay Description:Antagonist activity at human GPR55 expressed in CHO cells assessed as inhibition of lysophosphotidylinositol-induced beta-arrestin recruitment preinc...More data for this Ligand-Target Pair