BDBM50436082 CHEMBL2397103::US10273214, Example 1391

SMILES COc1ccc(OCC2N(CCc3cc(OC)c(OC)cc23)C(=O)c2cccc(Br)c2)cc1

InChI Key InChIKey=PPVAJUMVCCYQCV-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50436082   

TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50436082(CHEMBL2397103 | US10273214, Example 1391)
Affinity DataEC50:  900nMAssay Description:Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50436082(CHEMBL2397103 | US10273214, Example 1391)
Affinity DataIC50:  2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2C(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50436082(CHEMBL2397103 | US10273214, Example 1391)
Affinity DataIC50:  1.00E+3nMAssay Description:The assay involves using a cell line that expresses the NR1 subunit together with either NR2C or NR2D. These cell lines can be prepared by transfecti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1/2D(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50436082(CHEMBL2397103 | US10273214, Example 1391)
Affinity DataEC50:  2.20E+3nMAssay Description:Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed