BDBM50436122 CHEMBL2397471

SMILES CC(C)C[C@@H](NC(=O)[C@H]1CSSC[C@H]2NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](N)CSSC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H]3CCCN3C(=O)[C@@H](C)NC(=O)[C@@H](CCCCN)NC2=O)[C@H](C)O)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@H](CCCN=C(N)N)C(=O)N1)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](Cc1cnc[nH]1)C(O)=O

InChI Key InChIKey=PETYOLVFAQBBFE-RHIJZEKDSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50436122   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Southwest University

Curated by ChEMBL
LigandPNGBDBM50436122(CHEMBL2397471)
Affinity DataIC50:  2.03E+4nMAssay Description:Inhibition of TMRA-p53 binding to MDM2 (25 to 109 amino acids) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Southwest University

Curated by ChEMBL
LigandPNGBDBM50436122(CHEMBL2397471)
Affinity DataKd:  2.65E+4nMAssay Description:Binding affinity to MDM2 (25 to 109 amino acids) (unknown origin) after 30 mins by surface plasmon resosnance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed