BDBM50437077 CHEMBL2403690
SMILES Fc1cccc(c1)C#Cc1nc2CCN(Cc2s1)C(=O)C1CC(F)(F)C1
InChI Key InChIKey=IXLFGTLICMOEJQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50437077
Affinity DataEC50: 2.5nMAssay Description:Positive allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as potentiation of L-glutamate-induced activity after 1 hr ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-glutamate-induced activity after 1 hr by...More data for this Ligand-Target Pair