BDBM50438162 CHEMBL2409880
SMILES OC[C@H]1C[C@@H](O)CCN1CCc1ccc(Nc2nc(cs2)-c2ccccc2F)cc1
InChI Key InChIKey=QRSGDELKVVKLLO-MOPGFXCFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50438162
Affinity DataIC50: 220nMAssay Description:Inhibition of purified human SphK2 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of purified human SphK1 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Inhibition of SphK1 in human WM266-4 cells assessed as inhibition of formation of [17C]-S1P formation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair