BDBM50438912 CHEMBL1096283::CVD-0012826::MAT-POS-1e0c1c67-1::US9073941, 619::Walrycin B

SMILES Cn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=XRVMPTWWKLKLPB-UHFFFAOYSA-N

Data  8 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50438912   

TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50438912(CHEMBL1096283 | CVD-0012826 | MAT-POS-1e0c1c67-1 |...)
Affinity DataEC50:  330nMAssay Description:Inhibition of TDP2 (unknown origin) using 4-nitrophenyl phenylphosphonate as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes of Health

LigandPNGBDBM50438912(CHEMBL1096283 | CVD-0012826 | MAT-POS-1e0c1c67-1 |...)
Affinity DataEC50:  3.55E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes of Health

LigandPNGBDBM50438912(CHEMBL1096283 | CVD-0012826 | MAT-POS-1e0c1c67-1 |...)
Affinity DataEC50:  3.55E+3nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed