BDBM50439190 CHEMBL2418788::US9126987, 6
SMILES CSc1nnc(o1)-c1ccc2[nH]cnc2c1
InChI Key InChIKey=JQJBZGYRDZXPJI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50439190
Affinity DataKi: 1.78E+4nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Escherichia coli DH5alpha using H-Gln-AMC as substrate by fluorometric analysis in presence of py...More data for this Ligand-Target Pair
Affinity DataKi: 1.78E+4nM ΔG°: -6.58kcal/mole IC50: 2.48E+4nMpH: 8.0 T: 2°CAssay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30 C. QC activity was evaluated fluorometricall...More data for this Ligand-Target Pair
Affinity DataIC50: 2.48E+4nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Escherichia coli DH5alpha using H-Gln-AMC as substrate by fluorometric analysis in presence of py...More data for this Ligand-Target Pair