BDBM50439297 CHEMBL2419523::US10696692, Example 311
SMILES CCC(=O)N1CCC(CC1)S(=O)(=O)c1ccc(CNC(=O)N2Cc3ccncc3C2)cc1
InChI Key InChIKey=UTPGHHUQELCXLE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50439297
Affinity DataIC50: 39.7nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human NAMPT using NAM/PRPP as substrate incubated for 15 mins prior to substrate addition measured after 30 mins by mass spectrometric ...More data for this Ligand-Target Pair