BDBM50439431 CHEMBL2420704

SMILES Cn1cc(c(n1)-c1ccc(F)cc1)-c1ccnc(c1)C1COCCN1

InChI Key InChIKey=ZVSNVLKUNCNJEG-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439431   

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439431(CHEMBL2420704)
Affinity DataIC50:  90nMAssay Description:Inhibition of human CK1 delta transfected in african green monkey cos7 cells after overnight incubation by whole cell assayMore data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439431(CHEMBL2420704)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of CK1 delta (unknown origin) using PLSRTLpSVASLPGL as substrate after 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439431(CHEMBL2420704)
Affinity DataIC50:  28nMAssay Description:Inhibition of CK1 epsilon (unknown origin) using PLSRTLpSVASLPGL as substrate after 85 mins by microplate reader analysisMore data for this Ligand-Target Pair