BDBM50439649 CHEMBL2419811::US9353075, 7
SMILES CCCCCCC[C@H](C)OC(=O)N[C@@H]1[C@H](C)OC1=O
InChI Key InChIKey=ROFODRYNJKSNQS-SDDRHHMPSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50439649
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 16nMpH: 7.4Assay Description:Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of C-terminal His-6-tagged recombinant human spleen NAAA enzyme expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 16nMAssay Description:Inhibition of Sprague Dawley rat lung native NAAA enzyme using heptadecenoylethanolamide as substrate preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 5nMpH: 4.5 T: 2°CAssay Description:NAAA protein preparation (10 ug) was pre-incubated with various concentrations of test compound or vehicle control in 100 mM NaH2PO4, 100 mM Tri Sodi...More data for this Ligand-Target Pair