BDBM50439946 CHEMBL2420287

SMILES CC(=O)N1CCN(CCOc2ccc(-c3cccc4c3oc(cc4=O)N3CCOCC3)c3sc4ccccc4c23)CC1

InChI Key InChIKey=SXBFFWXSDNBDGZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439946   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50439946(CHEMBL2420287)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human ERG expressed in cisapride treated CHO cells by Ion Works assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50439946(CHEMBL2420287)
Affinity DataEC50:  166nMAssay Description:Inhibition of DNA-PK autophosphorylation at S2056 in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50439946(CHEMBL2420287)
Affinity DataIC50:  2nMAssay Description:Inhibition of human DNA-PK using GST-tagged p53N66 as substrate after 1 hr by ELISA-based chemiluminiscence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed