BDBM50440323 CHEMBL2424833

SMILES COc1ccc2ncc(F)c([C@@H](O)[C@H](O)[C@@H]3CC[C@H](CO3)NCc3ccc4SCC(=O)Nc4n3)c2n1

InChI Key InChIKey=TWOGVSMCVZUIJI-FRALDWEZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440323   

TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440323(CHEMBL2424833)
Affinity DataIC50:  500nMAssay Description:Inhibition of wild type Staphylococcus aureus ATCC 29213 topoisomerase-4 subunit 2GrlA/2GrlB assessed as pBR322 relaxation after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440323(CHEMBL2424833)
Affinity DataIC50:  30nMAssay Description:Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed