BDBM50441626 GLABRIDIN::US9783551, Compound 1

SMILES CC1(C)Oc2ccc3C[C@@H](COc3c2C=C1)c1ccc(O)cc1O

InChI Key InChIKey=LBQIJVLKGVZRIW-ZDUSSCGKSA-N

Data  1 KI  4 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50441626   

TargetCytochrome P450 3A4(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50441626(GLABRIDIN | US9783551, Compound 1)
Affinity DataKi:  7.00E+3nMAssay Description:Mechanism based inhibition of human cytochrome P450 CYP3A4 measured by 7BFC O-debenzylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50441626(GLABRIDIN | US9783551, Compound 1)
Affinity DataIC50:  90nMAssay Description:Inhibition of tyrosinase (unknown origin) using L-tyrosine as substrate preincubated for 5 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Glaceum

US Patent
LigandPNGBDBM50441626(GLABRIDIN | US9783551, Compound 1)
Affinity DataIC50:  4.60E+4nMAssay Description:The degree of inhibition activity for PTP1B was investigated by using 2 mM p-nitrophenyl phosphate (p-NPP) as a substrate to measure the dephosphoryl...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Glaceum

US Patent
LigandPNGBDBM50441626(GLABRIDIN | US9783551, Compound 1)
Affinity DataIC50:  7.34E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Glaceum

US Patent
LigandPNGBDBM50441626(GLABRIDIN | US9783551, Compound 1)
Affinity DataIC50:  4.80E+4nMAssay Description:The degree of inhibition activity for PTP1B was investigated by using 2 mM p-nitrophenyl phosphate (p-NPP) as a substrate to measure the dephosphoryl...More data for this Ligand-Target Pair
In DepthDetails US Patent