BDBM50442158 CHEMBL2441111

SMILES COc1ccc2nc(Nc3cc(nc(n3)N3CCC[C@H]3C(N)=O)C(F)(F)c3ccc(F)cc3)sc2c1

InChI Key InChIKey=KBSZCUYNEUTCRR-KRWDZBQOSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442158   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50442158(CHEMBL2441111)
Affinity DataKi:  3.98E+3nMAssay Description:Inhibition of recombinant human FLAG-tagged ITK using biotinylated GST-SAM68 as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50442158(CHEMBL2441111)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of Aurora-B (unknown origin) using 5FAM-PKAtide as substrate after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed