BDBM50442817 CHEMBL2440737

SMILES NCc1ccc(cc1-c1cccc(c1)C(=O)OCC1CCCO1)C(=O)Nc1ccncc1F

InChI Key InChIKey=QTMQGFVLXXWUDA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50442817   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Agoralaan Abis

Curated by ChEMBL
LigandPNGBDBM50442817(CHEMBL2440737)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Agoralaan Abis

Curated by ChEMBL
LigandPNGBDBM50442817(CHEMBL2440737)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of ROCK2 (unknown origin) using long S6 kinase peptide as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Agoralaan Abis

Curated by ChEMBL
LigandPNGBDBM50442817(CHEMBL2440737)
Affinity DataIC50:  49nMAssay Description:Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed