BDBM50446228 CHEMBL3109061

SMILES [#6]C([#6])([#6])[#8]-[#6](=O)-[#7]-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7]-[#6](=O)-[#8]-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#8]-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@H]-1-[#6]-[#8]-[#6@@H]-2-[#6@@H](-[#6]-[#8]-[#6@H]-1-2)-[#8]-[#6]-c1ccccc1

InChI Key InChIKey=XCLWZPPKPAYIQR-KKYNAJBLSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50446228   

TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universidade Federal Do Abc

Curated by ChEMBL
LigandPNGBDBM50446228(CHEMBL3109061)
Affinity DataKi:  1.70E+3nMAssay Description:Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universidade Federal Do Abc

Curated by ChEMBL
LigandPNGBDBM50446228(CHEMBL3109061)
Affinity DataKi:  2.40E+3nMAssay Description:Competitive inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Universidade Federal Do Abc

Curated by ChEMBL
LigandPNGBDBM50446228(CHEMBL3109061)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of human recombinant KLK7 expressed in baculovirus-infected insect cell system using Abz-KLYSSKQ-Eddnp as substrate incubated for 5 mins p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Universidade Federal Do Abc

Curated by ChEMBL
LigandPNGBDBM50446228(CHEMBL3109061)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated for 5 mins p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed