BDBM50447012 CHEMBL1446389

SMILES N#CC(Nc1ccccc1)c1ccccc1OCc1ccccc1

InChI Key InChIKey=OCHKGCOPTZOXOP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50447012   

TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50447012(CHEMBL1446389)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of SMS2 (unknown origin) expressed in H5 insect cells using C6-NBD-Cer as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50447012(CHEMBL1446389)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of purified SMS2 (unknown origin) pre-incubated for 5 mins followed by DMPC and C6-NBD-ceramide addition and measured after 30 mins by HPL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50447012(CHEMBL1446389)
Affinity DataIC50:  2.09E+4nMAssay Description:Inhibition of purified SMS2 (unknown origin) using C6-NBD-Ceramide and DMPC as substrates preincubated for 5 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50447012(CHEMBL1446389)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50447012(CHEMBL1446389)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of SMS2 (unknown origin) over-expressed in H5 insect cell lysate using C6-NBD-Ceramide and DMPC as substrates preincubated for 30 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50447012(CHEMBL1446389)
Affinity DataIC50:  2.09E+4nMAssay Description:Inhibition of purified SMS2 (unknown origin) using C6-NBD-Ceramide and DMPC as substrates preincubated for 5 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed