BDBM50447220 CHEMBL3113170::US10752581, Compound 50

SMILES COc1cccc(CNc2ccc(cc2)S(=O)(=O)Nc2nc(C)cs2)c1O

InChI Key InChIKey=GPPXZTIEQLOROW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50447220   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50447220(CHEMBL3113170 | US10752581, Compound 50)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50447220(CHEMBL3113170 | US10752581, Compound 50)
Affinity DataIC50:  330nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50447220(CHEMBL3113170 | US10752581, Compound 50)
Affinity DataIC50:  2.70E+3nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
In DepthDetails US Patent