BDBM50447517 CHEMBL3115894

SMILES NC(=N)c1ccc(CNC(=O)C(CCC2CCNCC2)NC(=O)[C@@H](CC2CCCCC2)NCC(O)=O)cc1

InChI Key InChIKey=QFGNPOOZZWIFBN-XMMISQBUSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50447517   

TargetVitamin K-dependent protein C(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50447517(CHEMBL3115894)
Affinity DataKi:  300nMAssay Description:Competitive inhibition of human APC using S-2366 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50447517(CHEMBL3115894)
Affinity DataKi: >1.90E+4nMAssay Description:Competitive inhibition of human coagulation factor 11a using S-2366 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50447517(CHEMBL3115894)
Affinity DataKi: >4.30E+4nMAssay Description:Competitive inhibition of human coagulation factor 10a using S-2765 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50447517(CHEMBL3115894)
Affinity DataIC50: >1.30E+5nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50447517(CHEMBL3115894)
Affinity DataIC50:  920nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50447517(CHEMBL3115894)
Affinity DataIC50: >4.40E+4nMAssay Description:Inhibition of human coagulation factor 11a using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed