BDBM50449384 CHEMBL3126351

SMILES CC(C)[C@H](Nc1nc2ccncc2c2c1cc[nH]c2=O)C(F)(F)F

InChI Key InChIKey=TVSDLBOZXLYNDG-ZDUSSCGKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50449384   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50449384(CHEMBL3126351)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant Jak2 (unknown origin) using biotinylated synthetic peptide substrate by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50449384(CHEMBL3126351)
Affinity DataIC50:  170nMAssay Description:Inhibition of Jak2 (unknown origin) assessed as inhibition of STAT5 phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed