BDBM50450046 CHEMBL4173974
SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3nc(CO)c(Cc4ccc(F)cc4)cc23)[C@@H](CN2CCOC[C@H]2C)CN1
InChI Key InChIKey=YCXOHEXZVKOGEV-DNRQZRRGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50450046
Affinity DataKi: 800nMAssay Description:Inhibition of Zika virus NS2B-NS3 proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length FLAG-tagged XIAP (unknown origin) interaction with full length untagged caspase-9 expressed in HEK293 cells after 2 hrs by ...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Taros Chemicals
Curated by ChEMBL
Taros Chemicals
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of CIAP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <40nMAssay Description:Inhibition of XIAP (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells incubated for 600 secs at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Taros Chemicals
Curated by ChEMBL
Taros Chemicals
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:Induction of intracellular cIAP1 degradation in human MDA-MB-231 cells after 2 hrsMore data for this Ligand-Target Pair