BDBM50450156 CHEMBL1933810

SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8]-[#6](-[#6])=O)[C@]1([#6])[#6]-[#6]-[#6@@H](-[#8])[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6]

InChI Key InChIKey=VJSLAEHMOUSVLS-MWTXHCMUSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50450156   

TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50450156(CHEMBL1933810)
Affinity DataEC50:  8.11E+3nMAssay Description:Inhibition of NF-kappaB stimulated STAT3 activation in human HeLa cells incubated with NF-kappaB for 16 hrs followed by compound addition measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50450156(CHEMBL1933810)
Affinity DataEC50:  4.33E+3nMAssay Description:Inhibition of IFNgamma-stimulated STAT3 activation in human HeLa cells incubated with IFNgamma for 16 hrs followed by compound addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50450156(CHEMBL1933810)
Affinity DataEC50:  6.92E+3nMAssay Description:Inhibition of NF-kappaB stimulated STAT3 activation in human AD293 cells incubated with NF-kappaB for 16 hrs followed by compound addition measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50450156(CHEMBL1933810)
Affinity DataEC50:  2.21E+3nMAssay Description:Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Macau

Curated by ChEMBL
LigandPNGBDBM50450156(CHEMBL1933810)
Affinity DataEC50:  1.18E+3nMAssay Description:Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed