BDBM50451132 CHEMBL2079586::WIN-35428

SMILES [H][C@@]12CC[C@]([H])([C@H]([C@H](C1)c1ccc(F)cc1)C(=O)OC)N2C

InChI Key InChIKey=QUSLQENMLDRCTO-TUVASFSCSA-N

Data  14 KI  42 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50451132   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50451132(CHEMBL2079586 | WIN-35428)
Affinity DataIC50:  759nMAssay Description:The compound was tested in vitro for binding affinity for the serotonin transporter (5-HTT) using competitive binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50451132(CHEMBL2079586 | WIN-35428)
Affinity DataIC50:  139nMAssay Description:The compound was tested in vitro for low binding affinity for the Dopamine transporter (DAT) using competitive binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50451132(CHEMBL2079586 | WIN-35428)
Affinity DataIC50:  2.60nMAssay Description:The compound was tested in vitro for high binding affinity for the Dopamine transporter (DAT) using competitive binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie

Curated by ChEMBL
LigandPNGBDBM50451132(CHEMBL2079586 | WIN-35428)
Affinity DataIC50:  834nMAssay Description:The compound was tested in vitro for binding affinity for the norepinephrine transporter (NET) using competitive binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed