BDBM50451297 CHEMBL4216551
SMILES COc1cc(ccc1Nc1ncc(Cl)c(Oc2ccc(NC(=O)\C=C\CN(C)C)cc2)n1)N1CCN(C)CC1
InChI Key InChIKey=KSJZGAARSPDRCW-AATRIKPKSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50451297
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of EGFR E746_A750 deletion/T790M mutant in human growth-resistant PC9 cells assessed as reduction in cell viability after 72 hrs by MTT as...More data for this Ligand-Target Pair
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of EGFR in human NCI-H460 cells assessed as reduction in cell viability after 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.07E+3nMAssay Description:Inhibition of EGFR E746_A750 deletion mutant in human PC9 cells assessed as reduction in cell viability after 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of ABL T315I mutant in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of ABL in mouse BAF3 cells assessed as reduction in cell viability after 72 hrs by MTT assayMore data for this Ligand-Target Pair