BDBM50451631 CHEMBL4212454

SMILES CN(C#N)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)c1cc(nn1C)C(C)(C)C

InChI Key InChIKey=GWGYOEFAMBIJPC-INIZCTEOSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50451631   

TargetProcathepsin L(Homo sapiens (Human))
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50451631(CHEMBL4212454)
Affinity DataKi:  0.126nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50451631(CHEMBL4212454)
Affinity DataKi:  1.60nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
University Of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50451631(CHEMBL4212454)
Affinity DataKi:  1.60nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-phe-Arg-7-amido-4-methylcoumarin as substrate by fluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed