BDBM504520 9-ethyl-6,6-dimethyl-11-oxo-8- (pyrimidin-5-yl)-6,11-dihydro-5H- benzo[b]carbazole-3-carbonitrile::US11066363, Compound 16

SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1-c1cncnc1

InChI Key InChIKey=FFYSPCYXAGHVFZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504520   

TargetSRSF protein kinase 2(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM504520(9-ethyl-6,6-dimethyl-11-oxo-8- (pyrimidin-5-yl)-6,...)
Affinity DataIC50:  12.5nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSRSF protein kinase 1(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM504520(9-ethyl-6,6-dimethyl-11-oxo-8- (pyrimidin-5-yl)-6,...)
Affinity DataIC50:  2.53nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent