BDBM50452455 CHEMBL4215510

SMILES CC(C)Nc1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)N[C@@H](CO)C(C)C)c2cc(cnc2n1)-c1cccc(F)c1

InChI Key InChIKey=JVPUVRRKNUBWPR-ZDXQCDESSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452455   

TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50452455(CHEMBL4215510)
Affinity DataEC50:  98nMAssay Description:Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50452455(CHEMBL4215510)
Affinity DataEC50:  43nMAssay Description:Agonist activity at rat NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 15 mins by fluorescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed