BDBM50452523 CHEMBL4212349

SMILES COc1ccc2cc(ccc2c1)[C@@]1(C[C@H](N(C1)C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)C1CC1)OC

InChI Key InChIKey=NPDJDVOYYRDYDC-IBDGMSGISA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452523   

TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452523(CHEMBL4212349)
Affinity DataEC50:  55nMAssay Description:Inhibition of HCV genotype 1a H77 NS3 protease infected in human HuH7 replicon cells assessed as reduction in viral replication after 4 days by lucif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50452523(CHEMBL4212349)
Affinity DataEC50:  34nMAssay Description:Inhibition of HCV genotype 1b Con1 NS3 protease infected in human HuH7 replicon cells assessed as reduction in viral replication after 4 days by luci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed