BDBM50453185 CHEMBL4203825

SMILES CCN1CCN(CC1)c1ccc(Nc2nc(N[C@H]3CC[C@H](N)CC3)nc3n(cnc23)C2CCCC2)cc1

InChI Key InChIKey=AGAQJVYMHPGORF-AQYVVDRMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50453185   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50453185(CHEMBL4203825)
Affinity DataIC50:  3nMAssay Description:Inhibition of N-terminal GST/His6-fused recombinant human FLT3 (R571 to S993 residues) ITD mutant expressed in Sf9 insect cells using poly (Ala,Glu,L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50453185(CHEMBL4203825)
Affinity DataIC50:  2nMAssay Description:Inhibition of N-terminal GST/His6-fused recombinant human FLT3 (R571 to S993 residues) D835Y mutant expressed in Sf9 insect cells using poly (Ala,Glu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50453185(CHEMBL4203825)
Affinity DataIC50:  10nMAssay Description:Inhibition of N-terminal GST/His6-fused recombinant wild type human FLT3 (R571 to S993 residues) expressed in Sf9 insect cells using poly (Ala,Glu,Ly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed