BDBM50453747 CHEMBL4211672

SMILES CC(C)(C)c1ccc(OC(=O)c2sc3ccccc3c2Cl)c(c1)C(C)(C)C

InChI Key InChIKey=PCFVJTLSHOAJDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50453747   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50453747(CHEMBL4211672)
Affinity DataIC50:  800nMAssay Description:Inhibition of nuclease activity of APE1 in human glioblastoma cells assessed as reduction in AP site DNA cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed