BDBM50455747 CHEMBL4214872::US10829491, Compound S2

SMILES Nc1ncnc2n3C[C@H](CCc3c(-c3ccc(Oc4ccccc4)cc3)c12)NC(=O)C=C

InChI Key InChIKey=IZIKXPZHFAJJMS-KRWDZBQOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50455747   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Acad

US Patent
LigandPNGBDBM50455747(CHEMBL4214872 | US10829491, Compound S2)
Affinity DataIC50: <1nMAssay Description:Poly(Glu, Tyr) 4:1 as a substrate for enzyme catalyzed reaction was diluted with potassium-free PBS (10 mM sodium phosphate buffer, 150 mM NaCl, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Acad

US Patent
LigandPNGBDBM50455747(CHEMBL4214872 | US10829491, Compound S2)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed