BDBM50455747 CHEMBL4214872::US10829491, Compound S2
SMILES Nc1ncnc2n3C[C@H](CCc3c(-c3ccc(Oc4ccccc4)cc3)c12)NC(=O)C=C
InChI Key InChIKey=IZIKXPZHFAJJMS-KRWDZBQOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50455747
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Acad
US Patent
Shanghai Institute of Materia Medica, Chinese Acad
US Patent
Affinity DataIC50: <1nMAssay Description:Poly(Glu, Tyr) 4:1 as a substrate for enzyme catalyzed reaction was diluted with potassium-free PBS (10 mM sodium phosphate buffer, 150 mM NaCl, pH 7...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Acad
US Patent
Shanghai Institute of Materia Medica, Chinese Acad
US Patent
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant human BTK using Poly(Glu, Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair