BDBM50456401 IRIGENOL
SMILES Oc1cc(cc(O)c1O)-c1coc2cc(O)c(O)c(O)c2c1=O
InChI Key InChIKey=DFURNQJNFBMYHM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50456401
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of RGS17 (unknown origin) GAP activity in presence of GTP by malachite green dye based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.72E+4nMAssay Description:Inhibition of wild type GST-tagged RGS17 (unknown origin) interaction with biotinylated Galphao after 30 mins in presence of AMF and GDP by AlphaScre...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University
Curated by ChEMBL
Chungnam National University
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataKd: 7.10E+5nMAssay Description:Binding affinity to RGS17 (unknown origin) by ITC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8.18E+4nMAssay Description:Inhibition of RGS17 (unknown origin) C117A mutant interaction with biotinylated Galphao after 30 mins in presence of AMF and GDP by AlphaScreen assayMore data for this Ligand-Target Pair