BDBM50458224 CHEMBL2297871

SMILES O=C(C1CC1)c1ccc(OCCCN2CCCCC2)cc1

InChI Key InChIKey=GEURKKDLGWDNKE-UHFFFAOYSA-N

Data  8 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50458224   

TargetHistamine H3 receptor(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50458224(CHEMBL2297871)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]iodoproxyfan from human H3R expressed in CHOK1 cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Medical University

Curated by ChEMBL
LigandPNGBDBM50458224(CHEMBL2297871)
Affinity DataKi:  4nMAssay Description:Binding affinity to Rattus norvegicus (rat) H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50458224(CHEMBL2297871)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3R expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50458224(CHEMBL2297871)
Affinity DataKi:  11nMAssay Description:Displacement of [3H] N-alpha methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells measured after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50458224(CHEMBL2297871)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50458224(CHEMBL2297871)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]MSX-2 from human recombinant adenosine A2A receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50458224(CHEMBL2297871)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PSB-603 from human recombinant adenosine A2B receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50458224(CHEMBL2297871)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PSB-11 from human recombinant adenosine A3 receptor expressed in CHO cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50458224(CHEMBL2297871)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected insect cell membranes using kynuramine as substrate after 15 to 20 mins by discontinuous ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Heinrich Heine University Duesseldorf

Curated by ChEMBL
LigandPNGBDBM50458224(CHEMBL2297871)
Affinity DataIC50:  3.88E+3nMAssay Description:Inhibition of human MAO-B expressed in baculovirus infected insect cell membranes using kynuramine as substrate after 15 to 20 mins by discontinuous ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed