BDBM50458226 CHEMBL4217355
SMILES Brc1ccc(COc2ccc3C\C(=C/c4ccc(OCCCN5CCCCC5)cc4)C(=O)c3c2)cc1
InChI Key InChIKey=LZUBTFVEEDSMJZ-LGUFXXKBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50458226
TargetHistamine H3 receptor(Homo sapiens (Human))
Heinrich Heine University Duesseldorf
Curated by ChEMBL
Heinrich Heine University Duesseldorf
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3R expressed in HEK293 cell membranes after 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Heinrich Heine University Duesseldorf
Curated by ChEMBL
Heinrich Heine University Duesseldorf
Curated by ChEMBL
Affinity DataIC50: 5.51E+3nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected insect cell membranes using kynuramine as substrate after 15 to 20 mins by discontinuous ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Heinrich Heine University Duesseldorf
Curated by ChEMBL
Heinrich Heine University Duesseldorf
Curated by ChEMBL
Affinity DataIC50: 232nMAssay Description:Inhibition of human MAO-B expressed in baculovirus infected insect cell membranes using kynuramine as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Heinrich Heine University Duesseldorf
Curated by ChEMBL
Heinrich Heine University Duesseldorf
Curated by ChEMBL
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of human MAO-B expressed in baculovirus infected insect cell membranes using kynuramine as substrate after 15 to 20 mins by discontinuous ...More data for this Ligand-Target Pair