BDBM50459398 CHEMBL4204210
SMILES CN(C)C(=S)[C@@H]1CCCN1C(=O)NCc1ccc(cc1C)C(=O)N1Cc2cnn(C)c2Nc2ccccc12
InChI Key InChIKey=AOPORIRPXVMWSL-DEOSSOPVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50459398
Affinity DataKi: 226nMAssay Description:Displacement of DY647 from SNAP-tagged OTR receptor (unknown origin) expressed in HEK293 cells by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.25E+3nMAssay Description:Displacement of DY647 from SNAP-tagged V1A receptor (unknown origin) expressed in HEK293 cells by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.67E+3nMAssay Description:Displacement of DY647 from SNAP-tagged V2 receptor (unknown origin) expressed in HEK293 cells by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Agonist activity at mouse OTR receptor expressed in HEK293FT cells assessed as stimulation of calcium release by Aequorin based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Agonist activity at human OTR receptor expressed in HEK293FT cells assessed as stimulation of calcium release by Aequorin based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human V1A receptor expressed in HEK cells assessed as inhibition of AVP-induced intracellular calcium flux incubated for 45 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at human V1a receptor expressed in HEK293FT cells assessed as inhibition of AVP-induced calcium release by Aequorin based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 62nMAssay Description:Agonist activity at human OTR receptor expressed in HEK293FT cells incubated for 30 mins by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at human V1a receptor expressed in HEK293FT cells assessed as inhibition of AVP-induced response incubated for 30 mins by beta-ar...More data for this Ligand-Target Pair
Affinity DataEC50: 660nMAssay Description:Agonist activity at human V2 receptor expressed in HEK293FT cells incubated for 30 mins by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:Agonist activity at human V2 receptor expressed in HEK293FT cells assessed as stimulation of calcium release by Aequorin based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Agonist activity at human OTR expressed in HEK cells assessed as increase in intracellular calcium flux incubated for 45 mins by Indo1-AM dye based f...More data for this Ligand-Target Pair