BDBM50459424 CHEMBL64880

SMILES Cc1cc2nc(N3CCNCC3)n(Cc3ccccc3)c2cc1C

InChI Key InChIKey=HBJFQCBYCFIBOI-UHFFFAOYSA-N

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50459424   

Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50459424(CHEMBL64880)
Affinity DataKi:  2nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Faes

Curated by ChEMBL
LigandPNGBDBM50459424(CHEMBL64880)
Affinity DataKi:  2nMAssay Description:Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonistMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50459424(CHEMBL64880)
Affinity DataKi: <1.00E+3nMAssay Description:In vitro by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor on rat cortical membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50459424(CHEMBL64880)
Affinity DataKi: <1.00E+3nMAssay Description:In vitro by displacement of [3H]raclopride from Dopamine receptor D2 on rat striatal membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Faes

Curated by ChEMBL
LigandPNGBDBM50459424(CHEMBL64880)
Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity was evaluated in vitro by displacement of [3H]ketanserin from 5-hydroxytryptamine 2A receptor on rat cortical membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Faes

Curated by ChEMBL
LigandPNGBDBM50459424(CHEMBL64880)
Affinity DataKi: <1.00E+3nMAssay Description:In vitro by displacement of [3H]GR-113808 from 5-hydroxytryptamine 4 receptor on guinea pig striatal membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSon of sevenless homolog 1(Homo sapiens (Human))
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50459424(CHEMBL64880)
Affinity DataEC50:  8.60E+3nMAssay Description:Activation of human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS comple...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed